Psalms 76:10 (KJV) Surely the wrath of man shall praise thee: the remainder of wrath shalt thou restrain.
What does someone really gain in defying God? Nothing–there’s nothing to gain but everything to lose. It may give some sense of pride and control; pride because he’s not bowing before anyone, control because he’s doing what he wants to do, but both positions are flawed and false. God is God, whether one recognizes it or not. He is infinitely greater than anyone and He is the One really in control of everything. Even one’s rebellion, no matter how bold and blatant, is working against the rebel and ultimately for God’s glory. Nothing planned against God will prosper.
No one who fights against Him will win. History speaks: voices have been raised in opposition to God, some louder than others, some heeded more than others. They may have been known during their times; their opinions may have been widely popular; their reach may have been global, but their names and impact are barely felt or recognized now. They’ve come and they’ve gone; they’ve risen and they’ve fallen; God is still God; He still lives; He’s still reigning, unthreatened.
Any seeming success anyone has in campaigning against God can only be considered success when assessed within the realm of the earthly. God can be the most unpopular or even the most hated entity in the world, but His rule extends way far bigger than this world. He’s never shaken by that. Its easy for Him to work with a remnant–a small group of faithful, devoted, committed followers–people who aren’t influenced by the ungodliness that pervades their environment. We are the remnant. There are “God-defyers;” there is us. God is in total control of both.